Freeze Dryer

LABORATORY & INDUSTRIAL FREEZE DRYER (LYOPHILIZER)

The Freeze Dryer (Lyophilizer) is a device that allows the drying of materials without the need to heat them. The physical principle involved in lyophilization is sublimation, which is the direct passage from the solid to the gaseous state, without passing through the liquid state. For the process to take place, the frozen product is dried under vacuum, without thawing.

 

FREEZE-DRYING PROCESS EQUIPMENT

How does the freeze-drying process work? In general, lyophilization is a process that consists of removing water (and other solvents) from a sample, through the sublimation process, which is the transition from a solid to a gaseous state, without going through a liquid state.

This process allows preserving the organoleptic characteristics, such as color, brightness, light, odor, texture and flavor, as well as the original shape of the product. So it can be easily restored when hydrated. Thus, as it works at low temperatures, it is also ideal for thermo-sensitive samples, such as enzymes. In addition, it preserves the samples by inhibiting enzymatic and oxidative reactions, which normally happen in the presence of water. It also increases the shelf life of products, which can be stored at room temperature for years.

In principle, to start lyophilization, the sample must be completely frozen. Right after the association of low temperature and pressure, it allows the solvent to be removed by sublimation. As a result, a product with a porous structure is obtained, as well as, free of moisture that can easily be reconstituted by adding water

 

The main steps of freeze-drying

ProcedureTime and purpose
1, Product cleaning10min, remove
2, Product peeling60min, remove the peel of some fruits
3, Product dicing/slicing30min cut the product into small size, <10mm
4, Product loading2min, loading cut product into trays
5, Product freezing3h, get the product completely frozen in the shortest time
6, Vapor condenser freezing30min, to catch vapor from sublimation
7, Vacuum chamber30min, to have an extremely low pressure
8, Heating product10-15h, to speed up the sublimation
9, Unloading2min, unload the finished product
10, Defrosting0.5-1h, defrost for next batch of production
11, Packing30min, packing product avoid regaining moisture

(for reference only, the time will be different as the difference of material)

 

USES OF OUR FREEZE DRYER (LYOPHILIZER):

  • Food Laboratory – Coffee, eggs, Fish, Fruit, and Juices
  • Pharmaceutical Industry — Medicines
  • Biotechnology
  • Dairy Industry – Milk & Curd
  • Sugar Cane Industry
  • Pet Food
  • Taxidermy
  • Florals
  • Documents Recovery –  Like Titanic ship Sink Documents Preservation
  • Research
  • Echinacea, Mussels, Shark Cartilage.
  • Cheese Yogurts & Meets

 

FREEZE DRYER IDEAL FOR THE FOOD INDUSTRY:

  • All Kind of lyophilized food
  • Gourmet Around the world
  • Infant food supplement & child snacks
  • Outdoor & traveling food
  • Fast Consumable Food
  • Natural Pigment Extract from fruits & vegetable
  • Natural Extract for healthcare product
  • Pets Food
  • Permanent Flower
  • Biological Products

 

The Nutrient Content of Fresh Fruits and Freeze-Dried Fruits

Strawberry freeze-dried with a heating temperature of 40°C, vacuum pressure <50Pa.

The Nutrient Content of Fresh Strawberry and FD Strawberry
Nutrient NameFresh StrawberryFreeze Dried Strawberry
Potassium (mg)131131
Vitamin C (mg)4746
Carotene (μg)3029
Phosphorus (mg)2727
Calcium (mg)1818
Magnesium (mg)1212
Carbohydrate (g)7.17.1
Vitamin A (mg)54.9
Sodium (mg)4.24.2
Iron (mg)1.81.8
Dietary fiber (g)1.11.1
Protein (g)10.9
Vitamin E (mg)0.710.7
Selenium (μg)0.70.7

 

FREEZE DRYER FOR LABORATORY, FOOD & PHARMACEUTICAL INDUSTRY:

In the food industry, this method stands out for preserving the nutritional quality of food. The so-called “astronaut food” is a light option (since up to 90% of water/solvents are removed from the product), nutritious, and which maintains the flavor and aroma of the product is natural. As well as in the research and pharmaceutical industries, it stands out for allowing the preservation of enzymes, yeasts, and other microorganisms. As well as blood derivatives, cells, vaccines, viruses, serums, algae, and others.

Among the advantages of this method are, for example, accurate dosage, low enzymatic activity, easy reconstitution, the possibility of sterile manufacture. As well as the most recent applications are: the preservation of flowers and animals, documents and books old or recovered from floods, taxidermy, bone banks, and tissues for implantation. Freeze dryer for removing water or organic solvents from a vacuum solution and allowing the water frozen in the material to pass directly from the solid to the gas phase without going through the liquid phase.

Yatherm Scientific’s Freeze Dryer is ideal for meeting freeze drying requirements in research and development laboratories. Our freeze dryers (lyophilizers} developed for lyophilization of biological, pharmaceutical, and food products and still work “scale up”. Our Becnchtop Freeze Dryers (Lyophilizers) are a high-performance lyophilization unit with a design that allows you to carry out the entire lyophilization process fully automatically, as well as to monitor it accurately. Thus, Yatherm Scientific presents the best performance for technology transfer activities in R&D centers.

 

FEATURES OF FREEZE DRYER (LYOPHILIZER)

User-friendlyValidation Ports
Digital PID controllerPrecise vacuum control
Corrosion-resistant constructionThe audiovisual alarm on the Display panel
CFC/HCFC free refrigeration,Temperature, pressure and time control system
Primary & secondary dryingSingle/Dual stages cooling
2 to 50 Liters ice capacities-40°C or -110°C temperature

 

SPECIFICATIONS OF FREEZE DRYER FOR PHARMACEUTICAL & FOOD INDUSTRY:

ModelYS – FD 3YS – FD 5YS – FD 10YS – FD 20YS – FD 30
Max. ice capacity3 L5 L10 L20 L30 L
Ice condenser performance2 L / 24 Hr3.5 L / 24 Hr6.5 L / 24 Hr14 L / 24 Hr20 L / 24 Hr
Cold trap temperature-40°C or below
Temperature SensorPT-100
ControlsFully automatic with temperature and vacuuming
ControllerPLC with HMI
Refrigeration SystemHCFC / CFC Free
Compressor1/3 HP hermetically sealed branded compressors
DefrostHeating defrost system
Pressure ControlFully automatic
Drain connectionIn Bottom behind the cooling unit
MOCExterior – GI powder Coated
Exterior top – SS 304/SS 316
Drying chamber – SS 304/SS316
Cold Trap Chamber – SS 304/SS316
Front Door/Top Cover  – Acrylic
Optional Fast freeze flasks, Fast freeze adaptor, Extra ports manifold
Vacuum pump, RS 232 printer interface, Stainless steel exterior
– IQ/OQ documentation, Chart recorder
Power SupplySingle-phase 220 V +/- 10%, 50/60 Hz

 

SPECIFICATIONS OF BIG SIZE FREEZE DRYER FOR FOOD INDUSTRY:

ModelYSFD-50YSFD-100YSFD-200YSFD-300
TypeConductive type
Ice capacity (kg/batch)50kg100kg200kg300kg
Condenser temperature (°C)-45°C-45°C-45°C-45°C
Shelf temperature (°C)-35 to 60-35 to 60-35 to 60-35 to 60
Product cooling placein placein placein placein place
Product cooling temperature-35°C-35°C-35°C-35°C
Number of shelves681011
Shelf dimension (m)1.2*0.71.6*0.82.01*12.3*1.2
Shelf spacing (mm)50505050
Heating/cooling mediumoiloiloiloil
Number of product trays12 pcs16 pcs60 pcs66 pcs
Tray dimension (mm)600*700800*800500*670766*600
RefrigerantR404aR404aR404aR404a
The way of coolingby airby airby waterby water
Ultimate vacuum level (Pa)10 Pa10 Pa10 Pa10 Pa
The way of defrostingby waterby waterby waterby water
Power requirement (kW)11kw19kw34kw50kw
Installation area (m2)9101520
Chamber dimension (m)2.6*1.2*23*1.4*2.13.7*2*2.24.4*2*2.5
Weight (kg)2000250035005500

 

TO LEARN MORE ABOUT FREEZE DRYER (LYOPHILIZER):

Did you still have doubts about the lyophilization process or about the specifications of our freeze dryer equipment? Get in touch and talk to one of our experts. Please consult us in order to select the right model.

 

WHY YATHERM SCIENTIFIC’S FREEZE DRYER:

 Yatherm Scientific is providing laboratory, various industries, and research studies products and equipment at best prices in India. The laboratory equipment sold by Yatherm Scientific has advanced technology and high quality. Consult our portfolio or ask for help from our sales team and we will be happy to find benchtop freeze dryer, laboratory and industrial equipment that meets your needs. We have a wide portfolio, including the immediate delivery of the best-selling models.